top of page

Summary

The organism’s first line of defence against viruses is the innate immune system. In mammals, viral infections trigger a very potent antiviral response, known as the type-I Interferon response. Our group is interested in understanding how cells control the activation of this antiviral defence mechanism and how this is regulated during development.

 

Latest research

sensing of transposable elements.jpeg

Sensing of transposable elements by the antiviral innate immune system

samir bellora.jpg

The role of ILF3 during the host translational shutoff

Embryoid body compressed (1).jpg

MiRNA-deficient embryonic stem cells acquire a functional IFN response

Activation of the type-I Interferon response remodels miRNA biogenesis

bottom of page