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The organism’s first line of defence against viruses is the innate immune system. In mammals, viral infections trigger a very potent antiviral response, known as the type-I Interferon response. Our group is interested in understanding how cells control the activation of this antiviral defence mechanism and how this is regulated during development.


Latest research

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Sensing of transposable elements by the antiviral innate immune system

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The role of ILF3 during the host translational shutoff

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MiRNA-deficient embryonic stem cells acquire a functional IFN response

Activation of the type-I Interferon response remodels miRNA biogenesis

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